Medications: 4 reasons not to crush a tablet
To prevent the gradual release of the molecule
"Extended-release forms are designed to release the substance gradually," explains the Belgian Poisons Center. "Crushing or opening them can cause an immediate release of the active ingredient, especially if the drug has a narrow therapeutic index."
Overdose or underdose
Sometimes the film surrounding the capsule is present to protect the active ingredient from stomach acid. It is said to be gastro-resistant. Opening it can therefore lead to an overdose or underdose, thus rendering the medication ineffective or toxic.
Internal irritation
"Some medicinal substances can be irritating," reminds the Belgian Poisons Control Center. "Opening a capsule and swallowing its contents can potentially cause irritation of the mouth, throat, or esophagus."
An alteration of the active substance
Exposure to light, or even contact with food, can cause the active substance to deteriorate, thus reducing the effectiveness of the drug.
To find out if you can split a tablet in half, always ask your doctor or pharmacist for advice. Indeed, "the presence of a score does not always mean that the tablet is scored, because the presence of an equal dose in each half is not necessarily guaranteed."
Please note: It is also not recommended to chew or suck a tablet unless this is clearly stated in the instructions.
SudOuest
